High Protein Italian Beef and Pasta Bake

Featured in: Weekend Rustic Kitchen Favorites

This satisfying Italian-American bake combines lean ground beef with whole wheat pasta, colorful vegetables, and a rich tomato sauce. Topped with melted mozzarella and Parmesan, it delivers 33g of protein per serving while keeping calories at 370. Ready in under an hour, this dish reheats beautifully for meal prep lunches or quick weeknight dinners.

Updated on Wed, 21 Jan 2026 12:30:00 GMT
Golden-brown, melted mozzarella and Parmesan cheese bubbling over a hearty Italian beef and whole wheat pasta bake in a glass baking dish. Save
Golden-brown, melted mozzarella and Parmesan cheese bubbling over a hearty Italian beef and whole wheat pasta bake in a glass baking dish. | birchwhisk.com

The smell of this baking always pulls everyone into the kitchen before I even call dinner. It started as a way to hit my protein goals while still eating something that felt like comfort food, and now my friends request it whenever they come over for movie nights.

Last winter I made this for my sister who was training for a half marathon and needed substantial meals. She texted me the next day saying she ate it for breakfast, lunch, and dinner because it just kept hitting the spot.

Ingredients

  • Whole wheat penne or rotini: The nutty flavor holds up better than white pasta and keeps you full longer with that extra fiber
  • Extra lean ground beef: I grab the 5% fat version when I find it on sale, but 10% works perfectly fine too
  • Onion, garlic, red bell pepper, mushrooms: This vegetable base creates such depth that nobody notices how many vitamins theyre eating
  • Baby spinach: Toss it in at the end so it wilts just enough to disappear into the sauce
  • Canned crushed tomatoes: I always keep a few extra cans in my pantry for those nights when cooking feels impossible
  • Tomato paste: This little tube concentrates all the tomato flavor without making the sauce watery
  • Dried oregano and basil: Dried herbs actually work beautifully here since theyll bloom in the oven
  • Chili flakes: Even if you are sensitive to heat, just a pinch wakes everything up
  • Part skim mozzarella: I have found the reduced fat version melts just as beautifully as full fat
  • Grated Parmesan: That salty umami punch makes every bite feel restaurant quality
  • Turkey pepperoni slices: Totally optional but adds such a fun pizza vibe with way less grease

Instructions

Product image
Easily spray or drizzle oil for roasting vegetables, air frying, sautéing, and dressing salads with controlled coverage.
Check price on Amazon
Get your oven ready:
Crank it to 200 degrees Celsius so it is fully preheated by the time everything is assembled
Cook the pasta:
Boil those whole wheat noodles until they are still slightly firm since they will finish cooking in the oven
Brown the beef:
Cook the meat in a big skillet until it is no longer pink, breaking it up into small crumbles as it sizzles
Add the vegetables:
Toss in the onion, garlic, bell pepper, and mushrooms, letting everything soften and become fragrant for about 7 minutes
Wilt the spinach:
Stir in those greens and watch them collapse into the mixture within just a minute
Build the sauce:
Pour in the crushed tomatoes and tomato paste, then season with oregano, basil, chili flakes, salt and pepper
Let it simmer:
Let everything bubble together for 5 minutes so the flavors have time to become friends
Combine everything:
Mix the cooked pasta into that beautiful beef and vegetable sauce until every noodle is coated
Transfer to baking dish:
Spread the mixture into a 23 by 33 centimeter pan that you have lightly greased
Add the cheese:
Sprinkle mozzarella and Parmesan all over the top, then arrange pepperoni slices if you are using them
Bake until bubbly:
Let it bake for 20 minutes until the cheese is melted and slightly golden in spots
Garnish and serve:
Top with fresh basil leaves right before bringing it to the table
Product image
Easily spray or drizzle oil for roasting vegetables, air frying, sautéing, and dressing salads with controlled coverage.
Check price on Amazon
A close-up of the High Protein Italian Beef and Pasta Bake, showing chunky ground beef, diced bell peppers, and spinach in rich red sauce. Pin it
A close-up of the High Protein Italian Beef and Pasta Bake, showing chunky ground beef, diced bell peppers, and spinach in rich red sauce. | birchwhisk.com

My roommate walked in while this was bubbling away and literally asked if we were having pizza night. That is when I knew this recipe was a permanent fixture in our rotation.

Make It Your Own

Sometimes I swap in chickpea pasta for even more protein or add black olives for that Mediterranean touch. The beauty is how well it adapts to whatever you have in the fridge.

Meal Prep Magic

This divides perfectly into six containers and reheats beautifully throughout the week. I actually prefer the flavors on day two when everything has had time to really settle together.

Serving Suggestions

A crisp green salad with a simple vinaigrette cuts through the richness and makes the meal feel complete.

  • Keep some extra red pepper flakes on the table for heat lovers
  • A glass of cold milk or light beer pairs surprisingly well
  • Garlic bread on the side never hurt anyone
Product image
Dries dishes, utensils, and cookware neatly after cooking, keeping your countertop organized and clutter free.
Check price on Amazon
A rustic family-style serving of the cheesy Italian-American pasta bake with a side salad, fresh basil garnish, and steam rising from the surface. Pin it
A rustic family-style serving of the cheesy Italian-American pasta bake with a side salad, fresh basil garnish, and steam rising from the surface. | birchwhisk.com

There is something deeply satisfying about serving a dish that tastes indulgent but fuels you properly. This is the kind of comfort food that leaves you feeling good instead of sluggish.

Frequently Asked Questions

Can I freeze this pasta bake?

Yes, assemble the entire dish, cover tightly, and freeze for up to 3 months. Thaw overnight in the refrigerator before baking as directed, or bake from frozen adding 15-20 minutes to the cooking time.

What other vegetables work well in this bake?

Zucchini, eggplant, black olives, or artichoke hearts make excellent additions. Add them when sautéing the other vegetables so they soften properly. For extra nutrients, consider shredded carrots or chopped broccoli.

How can I increase the protein content further?

Stir in 200g of low-fat cottage cheese or ricotta before baking. You can also use legume-based pasta like chickpea or lentil pasta, which naturally contains more protein than wheat varieties.

Is this suitable for meal prep?

Absolutely. Portion into individual containers after cooling. Refrigerate for up to 4 days or freeze for longer storage. Reheat in the microwave with a splash of water to prevent drying, or warm in a 350°F oven until heated through.

Can I make this gluten-free?

Use gluten-free pasta made from rice, corn, or quinoa. Alternatively, chickpea or lentil pasta works beautifully and adds extra protein. Always check that your tomato paste, seasonings, and processed meats are certified gluten-free.

What can I substitute for the ground beef?

Ground turkey, chicken, or Italian sausage work well. For a vegetarian version, use plant-based crumbles or add extra vegetables and beans like cannellini or chickpeas for protein.

High Protein Italian Beef and Pasta Bake

Hearty beef and pasta bake loaded with vegetables and melty cheese, perfect for satisfying family dinners or meal prep.

Prep Time
20 Minutes
Cook Time
30 Minutes
Total Time
50 Minutes


Difficulty: Easy

Cuisine: Italian-American

Yield: 6 servings

Dietary: None specified

Ingredients

Pasta

01 10.5 oz whole wheat penne or rotini

Beef & Vegetables

01 1 lb extra-lean ground beef
02 1 medium onion, diced
03 2 cloves garlic, minced
04 1 red bell pepper, diced
05 3.5 oz mushrooms, sliced
06 3.5 oz baby spinach

Sauce

01 24 oz canned crushed tomatoes
02 2 tbsp tomato paste
03 1 tsp dried oregano
04 1 tsp dried basil
05 ½ tsp chili flakes
06 Salt and freshly ground black pepper, to taste

Cheese & Toppings

01 5 oz part-skim mozzarella cheese, shredded
02 1 oz grated Parmesan cheese
03 1 oz turkey pepperoni slices
04 Fresh basil, for garnish

Instructions

Step 01

Preheat Oven: Preheat oven to 400°F.

Step 02

Cook Pasta: Cook pasta in a large pot of boiling salted water until al dente. Drain and set aside.

Step 03

Brown Ground Beef: In a large nonstick skillet over medium heat, cook the ground beef until browned, breaking it up as it cooks. Drain excess fat if needed.

Step 04

Sauté Vegetables: Add onion, garlic, bell pepper, and mushrooms to the skillet. Sauté for 5–7 minutes until softened.

Step 05

Add Spinach: Stir in spinach and cook until wilted, about 1 minute.

Step 06

Prepare Sauce: Add crushed tomatoes, tomato paste, oregano, basil, chili flakes, salt, and pepper. Simmer for 5 minutes, allowing flavors to meld.

Step 07

Combine Pasta and Sauce: Combine the cooked pasta with the beef and vegetable sauce mixture.

Step 08

Transfer to Baking Dish: Transfer the mixture to a lightly greased 9x13 inch baking dish.

Step 09

Add Cheese Topping: Sprinkle mozzarella and Parmesan evenly over the top. Arrange turkey pepperoni slices if using.

Step 10

Bake: Bake for 20 minutes, until cheese is melted and bubbly.

Step 11

Garnish and Serve: Garnish with fresh basil before serving, if desired.

Tools You'll Need

  • Large pot
  • Large nonstick skillet
  • 9x13 inch baking dish
  • Mixing spoon
  • Cheese grater

Allergy Information

Please check ingredients for potential allergens and consult a health professional if in doubt.
  • Contains wheat (pasta)
  • Contains milk (cheese, optional cottage/ricotta cheese)
  • May contain soy (check processed meat or cheese labels)

Nutrition Facts (Per Serving)

It is important to consider this information as approximate and not to use it as definitive health advice.
  • Calories: 370
  • Total Fat: 11 g
  • Total Carbohydrate: 37 g
  • Protein: 33 g